Hi! This sounds like a great webinar. My cancer was also stage 111C ( primary peritoneal epithelial serous) of gynaecological origin but cells were undifferentiated. I had gene testing Feb. 2015. A rare variant was detected. A deletion and insertion in exon 18 of the BRCA gene was detected. This variant is predicted to cause an in-frame deletion of four amino acids from codon 2679 to codon 2682. To their knowledge, this variant was not listed in any databases.They re-tested to confirm their results. It could be categorized as an ACMG 3 variant or have no possible significance. No other variances on the BRCA genes were found when tested. My mother died from breast cancer and my female cousin had breast cancer. It is unknown if either had/ has genetic mutations. ( Two out of four females in my family). My questions to you are : 1. Are there any additional genetic tests available or beneficial to me now or would any family members"qualify" in Ontario, for testing now compared with 2015? 2. I didn't "qualify" for breast MRI's, because it isn't a known mutation. Has that changed in Ontario? 3. Would I, upon recurrence, be eligible and/or possibly benefit from a PARP inhibitor in Ontario? I don't expect you to discuss this in great depth, but I would like to be aware of my options for diagnostics and future treatment.
Thank you so much. Annika